ALZHEIMER'S DISEASE INHERITED THROUGH MATERNAL LINE, STUDY FINDS

A family history of Alzheimer's disease significantly increases the risk for developing this disorder, but a new study in Biological Psychiatry suggests that which of your parents has the disease is very important.

Alzheimer's is the most common form of dementia in late-life, affecting over 5 million elderly in the United States alone. In order to develop preventative treatments, it is necessary to identify those individuals who are at highest risk for developing Alzheimer's.

Although individuals with a parental history of Alzheimer's are at increased risk for developing the disease, the specific biological and genetic mechanisms accounting for this increased risk are not known.

An important consideration may be a phenomenon called genomic imprinting, where the pattern of the inherited disease differs based on whether the risk genes are inherited from the mother or the father.

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PRENATAL EXPOSURE TO NICOTINE AFFECTS STEM CELLS IN HIPPOCAMPUS

Prolonged prenatal exposure to nicotine decreases the number of newborn cells in the hippocampus, a brain area important in learning and memory, according to preliminary research presented at Neuroscience 2010, the annual meeting of the Society for Neuroscience, held in San Diego. The study offers a neurobiological explanation for why the children of women who smoke during pregnancy are at an increased risk of developing learning disabilities.

"Previous research has shown that nicotine, cocaine, and other addictive drugs decrease the number of newborn cells in adults. Our research suggests that these effects may be even more dramatic in newborn animals," said Robin Lester, PhD, of the University of Alabama at Birmingham, who directed the study. "These findings provide further warnings to expectant mothers that they should seek help in refraining from smoking during pregnancy," Lester said.

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PERIODIZATION OF CHILD DEVELOPMENT

Period means the circle of time. In this case, the period is periodization. This is a way to facilitate understanding of child development, namely by determining the stages of child's age to be educated in accordance with the physical and psychological condition.

The development is a process from childhood to reach maturity and character of progress or perfection of personality. In other words, development is the emergence of new things, for example, children who initially self-centered, it will eventually turn into a social, and if it was once full of fantasy life, in time they would like reality.

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