PARENTAL INFERTILITY AND CEREBRAL PALSY IN CHILDREN BORN SPONTANEOUSLY OR AFTER IVF/ICSI

Doctors have known for some time that children born after fertility treatments such as in vitro fertilisation (IVF) or intracytoplasmic sperm injection (ICSI) are at increased risk of cerebral palsy. However, it was not known whether this risk was due to the treatment itself, the higher frequency of preterm or multiple births, or a mechanism associated with couples' underlying infertility.

Now, new research published online in the journal Human Reproduction indicates that underlying infertility is not the main reason for the increased risk seen in IVF/ICSI children.

The study led by Dr. Jin Liang Zhu, an epidemiologist at the Danish Epidemiology Science Centre at the University of Aarhus, Denmark, is the first to examine the association between the time it takes a couple to achieve a pregnancy and the risk of cerebral palsy.

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BRAIN SCAN CAN PREDICT THERAPY RESPONSE FOR ANXIOUS KIDS

Experts say a brain scan can predict which kids with anxiety disorders will respond to one form of psychotherapy. As a consequence, Georgetown University neuroscientists say the use of psychiatric medication is not necessary for certain children.

Their study, presented at the annual meeting of the Society for Neuroscience in San Diego, utilized functional Magentic Resonance Imaging (fMRI) to map regions of brain activity. The results showed that children and adolescents, ages 8 to 16, who show fear when looking at happy faces on a screen were those who had least success with an eight-week course of cognitive-behavioral therapy.

Conversely, children who showed fear while looking at fearful faces benefitted from the treatment, the researchers found.

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NEW 3-D MODEL OF RNA 'CORE DOMAIN' OF ENZYME TELOMERASE MAY OFFER CLUES TO CANCER, AGING

Telomerase is an enzyme that maintains the DNA at the ends of our chromosomes, known as telomeres. In the absence of telomerase activity, every time our cells divide, our telomeres get shorter. This is part of the natural aging process, as most cells in the human body do not have much active telomerase. Eventually, these DNA-containing telomeres, which act as protective caps at the ends of chromosomes, become so short that the cells die.

But in some cells, such as cancer cells, telomerase, which is composed of RNA and proteins, is highly active and adds telomere DNA, preventing telomere shortening and extending the life of the cell.

UCLA biochemists have now produced a three-dimensional structural model of the RNA "core domain" of the telomerase enzyme. Because telomerase plays a surprisingly important role in cancer and aging, understanding its structure could lead to new approaches for treating disease, the researchers say.

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ANTIBIOTIC TREATMENT FOR EAR INFECTIONS IN KIDS PROVIDES ONLY MODEST BENEFITS, STUDY FINDS

Using antibiotics to treat newly diagnosed acute ear infections among children is modestly more effective than no treatment, but comes with a risk of side effects, according to a new study designed to help advise efforts to rewrite treatment guidelines for the common illness.

Researchers found no evidence that name-brand antibiotics work any better in general than generic antibiotics and that careful examination of the eardrum by a clinician for signs of infection is critical for accurate diagnosis of acute ear infections. The study is published in the Nov. 17 edition of the Journal of the American Medical Association.

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ALZHEIMER'S DISEASE INHERITED THROUGH MATERNAL LINE, STUDY FINDS

A family history of Alzheimer's disease significantly increases the risk for developing this disorder, but a new study in Biological Psychiatry suggests that which of your parents has the disease is very important.

Alzheimer's is the most common form of dementia in late-life, affecting over 5 million elderly in the United States alone. In order to develop preventative treatments, it is necessary to identify those individuals who are at highest risk for developing Alzheimer's.

Although individuals with a parental history of Alzheimer's are at increased risk for developing the disease, the specific biological and genetic mechanisms accounting for this increased risk are not known.

An important consideration may be a phenomenon called genomic imprinting, where the pattern of the inherited disease differs based on whether the risk genes are inherited from the mother or the father.

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PHYSIOLOGICAL SIDE IN PERIODIZATION OF CHILD DEVELOPMENT

The scope of a life full of limitations, but felt complete peace with everything that full dependence, that was experienced by the child while in his mother's womb. When children are born into the world, child physical dependence on the mother ends and move to a freer world. In the new world, children will encounter things that are different from previous condition.

Sumadi Suryabrata states that in the early years, child development is still limited in the development of physical function. Children interpret that the development of their soul on the basis of function and development of bodily functions. Developments in the physical‘s side is the basis for development in the side of mental health. Mental development will go well if it is preceded by physical maturity.

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